Fig. 1 · Structure
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Tranilast sodium
Anti-allergic Agent
Tranilast sodium is an anti-allergic agent recognized for its ability to suppress the production of prostaglandin D2 with an IC50 value of 0.1 mM. This compound exhibits notable anti-inflammatory and immunomodulatory properties, making it valuable for studies exploring allergic responses and inflammation. Additionally, Tranilast sodium antagonizes angiotensin II, inhibiting its biological effects in vascular smooth muscle cells, thereby contributing to cardiovascular research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 104931-56-8 |
| Applications | Anti-allergic Agent |
| Formula | C18H16NNaO5 |
| Molecular Weight | 349.31 |
| Synonyms | MK-341 sodium; SB 252218 sodium |
| SMILES | O=C([O-])C1=CC=CC=C1NC(/C=C/C2=CC=C(OC)C(OC)=C2)=O.[Na+] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.