Fig. 1 · Structure

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trans-Cephalosporin

NDM-1 Inhibitor

Trans-Cephalosporin is a potent NDM-1 inhibitor, exhibiting an IC50 value of 0.13 μM. This compound effectively targets the New Delhi metallo-beta-lactamase-1 enzyme, playing a crucial role in overcoming antibiotic resistance. Trans-Cephalosporin is valuable in research applications focused on developing novel antimicrobial strategies and understanding resistance mechanisms in pathogenic bacteria.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2757462-75-0
Applications NDM-1 Inhibitor
Formula C16H14N2O4S3
Molecular Weight 394.49
SMILES
O=C(C(N12)=C(CSC3=NC4=CC=CC=C4S3)CS[C@]2([H])[C@@H](OC)C1=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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