trans-Cyclohexane-p-bis(C-OTs)

Catalog No.: A83601
Linker
trans-Cyclohexane-p-bis(C-OTs) is a linker compound utilized in the synthesis of targeted protein degradation agents such as PROTAC degrader dBAZ2. This reagent plays a crucial role in facilitating the conjugation of various bioactive molecules, enhancing their selectivity and efficacy in disrupting protein interactions. Its application is significant in research focused on protein homeostasis and the development of innovative therapeutic strategies in cancer and other diseases.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptiontrans-Cyclohexane-p-bis(C-OTs) is a linker compound utilized in the synthesis of targeted protein degradation agents such as PROTAC degrader dBAZ2. This reagent plays a crucial role in facilitating the conjugation of various bioactive molecules, enhancing their selectivity and efficacy in disrupting protein interactions. Its application is significant in research focused on protein homeostasis and the development of innovative therapeutic strategies in cancer and other diseases.
Product Information
Catalog NumA83601
FormulaC22H28O6S2
Molecular Weight452.58
CAS Number134424-54-7
SMILESCC1=CC=C(S(OC[C@H]2CC[C@@H](CC2)COS(C3=CC=C(C)C=C3)(=O)=O)(=O)=O)C=C1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

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