Fig. 1 · Structure

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trans-Cyclohexane-p-bis(C-OTs)

Linker

trans-Cyclohexane-p-bis(C-OTs) is a linker compound utilized in the synthesis of targeted protein degradation agents such as PROTAC degrader dBAZ2. This reagent plays a crucial role in facilitating the conjugation of various bioactive molecules, enhancing their selectivity and efficacy in disrupting protein interactions. Its application is significant in research focused on protein homeostasis and the development of innovative therapeutic strategies in cancer and other diseases.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 134424-54-7
Applications Linker
Formula C22H28O6S2
Molecular Weight 452.58
SMILES
CC1=CC=C(S(OC[C@H]2CC[C@@H](CC2)COS(C3=CC=C(C)C=C3)(=O)=O)(=O)=O)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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