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trans-Sulfo-SMCC

Catalog No.: A42892
ADC Linker
trans-Sulfo-SMCC is a non-cleavable crosslinker designed for antibody-drug conjugates (ADCs), known for its membrane permeability. This reagent facilitates stable linkage between antibodies and cytotoxic agents, enhancing therapeutic efficacy while ensuring targeted delivery. It is ideal for research applications focused on ADC development and the investigation of targeted drug delivery systems.
trans-Sulfo-SMCC 1286837-77-1 ADC Linker
Grouped product items
Size Price Stock Qty
5mg
$125.00
In stock
10mg
$200.00
In stock
25mg
$420.00
In stock
50mg
$655.00
In stock
100mg
$1,040.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptiontrans-Sulfo-SMCC is a non-cleavable crosslinker designed for antibody-drug conjugates (ADCs), known for its membrane permeability. This reagent facilitates stable linkage between antibodies and cytotoxic agents, enhancing therapeutic efficacy while ensuring targeted delivery. It is ideal for research applications focused on ADC development and the investigation of targeted drug delivery systems.
Product Information
Catalog NumA42892
FormulaC16H18N2O9S
Molecular Weight414.39
CAS Number1286837-77-1
SMILESO=C([C@H]1CC[C@H](CN2C(C=CC2=O)=O)CC1)ON3C(C(S(=O)(O)=O)CC3=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Antibody-drug Conjugates (ADC) > ADC Linker