Fig. 1 · Structure
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Treprostinil diethanolamine
EP2/DP1/IP Agonist
Treprostinil diethanolamine is a potent agonist of the EP2, DP1, and IP receptors, exhibiting Ki values of 3.6 nM for EP2, 4.4 nM for DP1, and 32.1 nM for IP. This compound plays a critical role in elevating cAMP levels, contributing to vascular homeostasis. Treprostinil diethanolamine is particularly effective in inducing vasodilation of human pulmonary arteries, making it a valuable reagent for research in cardiovascular and pulmonary disease pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 830354-48-8 |
| Applications | EP2/DP1/IP Agonist |
| Formula | C27H45NO7 |
| Molecular Weight | 495.65 |
| Synonyms | UT-15C |
| SMILES | O=C(O)COC1=C2C[C@@]3([H])C[C@@H](O)[C@H](CC[C@@H](O)CCCCC)[C@@]3([H])CC2=CC=C1.OCCNCCO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.