Fig. 1 · Structure

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Treprostinil palmitil

Pulmonary Vasodilator Prodrug

Treprostinil palmitil is a long-acting pulmonary vasodilator prodrug that targets the inhibition of hypoxia-induced pulmonary vasoconstriction. Formulated in lipid nanoparticles, it exhibits sustained lung presence while minimizing systemic exposure. Research applications include the investigation of pulmonary arterial hypertension and interstitial lung disease, as well as the capacity to inhibit pulmonary vascular remodeling induced by Su/Hx challenge in animal models. Additionally, Treprostinil palmitil is associated with cough induction.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1706528-83-7
Applications Pulmonary Vasodilator Prodrug
Formula C39H66O5
Molecular Weight 614.94
Synonyms INS-1009
SMILES
CCCCC[C@H](O)CC[C@@H]1[C@]2([H])[C@@](C[C@H]1O)([H])CC3=C(OCC(OCCCCCCCCCCCCCCCC)=O)C=CC=C3C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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