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TRG-192

GLS Inhibitor

TRG-192 is a potent and selective inhibitor of glutaminase (GLS) with an IC50 of 68 nM. By effectively decreasing intracellular glutamate levels, TRG-192 serves as a valuable tool for investigating metabolic pathways in non-small cell lung cancer. Its specificity towards GLS makes it particularly useful for exploring the role of glutamine metabolism in cancer cell growth and survival.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3080792-24-8
Applications	GLS Inhibitor
Formula	C₂₄H₂₀F₆N₈O₂S₂
Molecular Weight	630.59
SMILES	O=C(NCC1=NC=CC(C(F)(F)F)=C1)C2=NN=C(CCCCC3=NN=C(C(NCC4=NC=CC(C(F)(F)F)=C4)=O)S3)S2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.