Fig. 1 · Structure
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TRPA1 agonist-3
Cat. No.
A68775
CAS
3083086-77-2
TRPA1 Agonist
TRPA1 Agonist-3 is a selective agonist for the TRPA1 ion channel, displaying EC50 values of 50.05 μM for human TRPA1 and 314.04 μM for mouse TRPA1. This compound does not activate other transient receptor potential channels, including hTRPV1 and hTRPM8. TRPA1 Agonist-3 has demonstrated efficacy in alleviating inflammatory pain in mouse models, operating through a channel desensitization mechanism, making it a valuable tool for studying pain pathways and TRPA1-related pharmacology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 3083086-77-2 |
| Applications | TRPA1 Agonist |
| Formula | C14H18N2OS |
| Molecular Weight | 262.37 |
| SMILES | COCCCNC1=NC(C2=CC=C(C=C2)C)=CS1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.