TRPC Antagonist 1 is a potent antagonist of transient receptor potential channels, specifically targeting TRPC3, TRPC4, TRPC5, TRPC6, and TRPC7, with IC50 values of 2.4 μM, 12.2 μM, 7.6 μM, 2.9 μM, and 3.4 μM, respectively. This compound exhibits significant anti-glioblastoma activity in vitro, effectively inhibiting the proliferation of U87 cell lines. It serves as a valuable tool for exploring the role of TRPC channels in various biological processes and disease models.
TRPC Antagonist 1 is a potent antagonist of transient receptor potential channels, specifically targeting TRPC3, TRPC4, TRPC5, TRPC6, and TRPC7, with IC50 values of 2.4 μM, 12.2 μM, 7.6 μM, 2.9 μM, and 3.4 μM, respectively. This compound exhibits significant anti-glioblastoma activity in vitro, effectively inhibiting the proliferation of U87 cell lines. It serves as a valuable tool for exploring the role of TRPC channels in various biological processes and disease models.
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