Fig. 1 · Structure
Documents & Downloads
TRPC3/6-IN-3
Cat. No.
A68823
CAS
1366234-01-6
TRPC3/6 Blocker
TRPC3/6-IN-3 is a selective inhibitor of TRPC3 and TRPC6 channels, primarily targeting the regulation of calcium influx in cells. This compound exhibits significant biological activity in modulating vascular smooth muscle contraction and endothelial function, making it relevant for cardiovascular disease research. TRPC3/6-IN-3 offers a valuable tool for elucidating the roles of these channels in various pathophysiological conditions, contributing to the understanding of cardiovascular mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1366234-01-6 |
| Applications | TRPC3/6 Blocker |
| Formula | C18H21ClFN3OS |
| Molecular Weight | 381.90 |
| SMILES | O=C(N1[C@H]([C@H](CCC1)C)C)C2=C(C)SC(NC3=C(C=C(C=C3)Cl)F)=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.