TRPC3 agonist-1

Catalog No.: A68833
TRPC3 Agonist
TRPC3 agonist-1 is a selective and competitive agonist of the TRPC3 channel, acting primarily at the L2 binding site of human TRPC3. This compound enhances TRPC3 channel activity, making it valuable for research on calcium signaling pathways and related physiological processes. Its ability to modulate TRPC3 function can aid in investigations of various conditions, including neurological disorders and cardiovascular diseases.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTRPC3 agonist-1 is a selective and competitive agonist of the TRPC3 channel, acting primarily at the L2 binding site of human TRPC3. This compound enhances TRPC3 channel activity, making it valuable for research on calcium signaling pathways and related physiological processes. Its ability to modulate TRPC3 function can aid in investigations of various conditions, including neurological disorders and cardiovascular diseases.
Product Information
Catalog NumA68833
FormulaC22H23F3N4O3
Molecular Weight448.44
CAS Number1589567-51-0
SMILESO=C(N1CCC(C2=NC3=C(C4=CC=C(C(F)(F)F)C=C4)C(C)=NN3C(O)=C2)CC1)OCC
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