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TRPC4/5-IN-1

Name: TRPC4/5-IN-1
Brand: Adooq Bioscience
SKU: A68815
Availability: OutOfStock

Cat. No. A68815 CAS 3032263-08-1

TRPC4/5 Inhibitor

TRPC4/5-IN-1 is a selective inhibitor of the transient receptor potential channel 4 and 5 (TRPC4/5), exhibiting IC50 values of 2.06 μM and 0.54 μM, respectively. This compound demonstrates significant biological activity in modulating TRPC channel-mediated calcium influx, making it useful for investigations into proteinuric kidney diseases and skin inflammatory conditions. Its targeted inhibition offers potential insights into the underlying mechanisms of these pathologies and may aid in the development of novel therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3032263-08-1
Applications	TRPC4/5 Inhibitor
Formula	C₂₁H₂₁N₃O
Molecular Weight	331.41
SMILES	CCC1=CC=C(N(CC2=CC=CC=C2)C(NCC3=CC=CO3)=N4)C4=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.