Fig. 1 · Structure

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TRPM5 agonist-1

Cat. No. A68843 CAS 2768029-03-2

TRPM5 Agonist

TRPM5 agonist-1 is a potent TRPM5 agonist with a pEC50 of 8.1, demonstrating strong selectivity over related cation channels such as TRPM8, TRPV1, TRPV4, TRPA1, and TRPM4. This compound elicits a stimulatory effect on gastrointestinal transit in mouse models, making it valuable for studies focused on enhancing gastric motility. TRPM5 agonist-1 is suitable for research exploring the roles of TRPM5 in gastrointestinal physiology and motility regulation.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 2768029-03-2
Applications TRPM5 Agonist
Formula C11H7Cl2N3S2
Molecular Weight 316.23
SMILES
ClC1=CN=C(CNC2=CC3=C(C=C2Cl)C=NS3)S1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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