Signaling Pathway
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| Discription | TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist, with an IC50 of 0.2 nM, used in the research of neuropathic pain syndromes. |
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| Catalog Num | A19329 |
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| Formula | C26H26N2O2 |
| Molecular Weight | 398.5 |
| CAS Number | 259674-19-6 |
| SMILES | O=C([C@@H](N(CC1=CC=CC=C1)CC2=CC=CC=C2)CC3=CNC4=CC=CC=C43)OC |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 68 mg/mL (170.64 mM) | |
| Water | Insoluble | ||
| Ethanol | 19 mg/mL (47.67 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.09 mL | 125.47 mL | 250.94 mL |
| 0.5 mM | 5.02 mL | 25.09 mL | 50.19 mL |
| 1 mM | 2.51 mL | 12.55 mL | 25.09 mL |
| 5 mM | 0.5 mL | 2.51 mL | 5.02 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
