TRPM8 receptor agonist-1

Catalog No.: A68797
TRPM8 Receptor Agonist
TRPM8 receptor agonist-1 is a selective agonist for the TRPM8 receptor, known for its ability to induce the inward flow of calcium, sodium, and other ions, resulting in cell membrane depolarization and subsequent action potential generation. This compound plays a crucial role in activating pathways associated with the swallowing reflex, making it valuable for research on oropharyngeal dysphagia and related conditions. Its activation of TRPM8 receptors positions it as a significant tool for exploring ion channel dynamics and therapeutic approaches in dysphagic disorders.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
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Nature volume 551, pages639-643 (2017)
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Biological Activity
DescriptionTRPM8 receptor agonist-1 is a selective agonist for the TRPM8 receptor, known for its ability to induce the inward flow of calcium, sodium, and other ions, resulting in cell membrane depolarization and subsequent action potential generation. This compound plays a crucial role in activating pathways associated with the swallowing reflex, making it valuable for research on oropharyngeal dysphagia and related conditions. Its activation of TRPM8 receptors positions it as a significant tool for exploring ion channel dynamics and therapeutic approaches in dysphagic disorders.
Product Information
Catalog NumA68797
FormulaC21H32N2O4
Molecular Weight376.49
CAS Number2791281-99-5
SMILESCC([C@H]1[C@@](O)(C[C@@H](CC1)C)C(NCCC2=C(C=CC=C2)OCC(N)=O)=O)C
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