TRPV antagonist 1

Catalog No.: A68889
TRP Channel Antagonist
TRPV Antagonist 1 is a selective transient receptor potential vanilloid (TRPV) channel antagonist, exhibiting an IC50 of less than 250 nM. This compound effectively inhibits TRPV-mediated calcium influx, making it a valuable tool for investigating TRPV-related signaling pathways. It is applicable in research focused on pain, inflammation, and sensory neuron function, facilitating the study of TRPV channels in various biological contexts.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTRPV Antagonist 1 is a selective transient receptor potential vanilloid (TRPV) channel antagonist, exhibiting an IC50 of less than 250 nM. This compound effectively inhibits TRPV-mediated calcium influx, making it a valuable tool for investigating TRPV-related signaling pathways. It is applicable in research focused on pain, inflammation, and sensory neuron function, facilitating the study of TRPV channels in various biological contexts.
Product Information
Catalog NumA68889
FormulaC26H21F3N2O4S
Molecular Weight514.52
CAS Number1192871-27-4
SMILESO=C1C(C2=CC=C(OC(F)(F)F)C=C2)=C(/C=C/C3=CC=CC(OC)=C3OCC4CC4)N=C5N1C=CS5
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