TRPV4 agonist-1 free base is a selective agonist of the transient receptor potential vanilloid 4 (TRPV4) channel, demonstrating an EC50 of 60 nM in human TRPV4 calcium assays. This compound induces calcium influx and is instrumental in studies focused on the physiological roles of TRPV4 in nociception, osmoregulation, and cellular mechanotransduction. Research applications include investigating the channel's involvement in pain pathways and potential therapeutic targets for related disorders.
TRPV4 agonist-1 free base is a selective agonist of the transient receptor potential vanilloid 4 (TRPV4) channel, demonstrating an EC50 of 60 nM in human TRPV4 calcium assays. This compound induces calcium influx and is instrumental in studies focused on the physiological roles of TRPV4 in nociception, osmoregulation, and cellular mechanotransduction. Research applications include investigating the channel's involvement in pain pathways and potential therapeutic targets for related disorders.
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