TRPV4 agonist-1

Catalog No.: A68787
TRP Channel Agonist
TRPV4 agonist-1 is a selective agonist of the transient receptor potential vanilloid 4 (TRPV4) channel, exhibiting an EC50 of 60 nM in human TRPV4 calcium assays. This compound is primarily utilized in research to investigate TRPV4-mediated pathways, including physiological functions like osmosensation and nociception. Its ability to activate TRPV4 makes it valuable for studying various biological processes and potential therapeutic applications related to TRP channels.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTRPV4 agonist-1 is a selective agonist of the transient receptor potential vanilloid 4 (TRPV4) channel, exhibiting an EC50 of 60 nM in human TRPV4 calcium assays. This compound is primarily utilized in research to investigate TRPV4-mediated pathways, including physiological functions like osmosensation and nociception. Its ability to activate TRPV4 makes it valuable for studying various biological processes and potential therapeutic applications related to TRP channels.
Product Information
Catalog NumA68787
FormulaC25H23ClF2N4O2
Molecular Weight484.93
CAS Number2314467-60-0
SMILESO=C1N(C2=CC=C(OC3=CC=C(F)C=C3)C=C2)C(N4CCN(C)CC4)=NC5=C(F)C=CC=C51.Cl
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