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TRPV4 antagonist 4

Name: TRPV4 antagonist 4
Brand: Adooq Bioscience
SKU: A68794
Availability: OutOfStock

Cat. No. A68794 CAS 2918803-89-9

TRPV4 Antagonist

TRPV4 antagonist 4 is a selective TRPV4 antagonist with an IC50 value of 22.65 nM, effectively inhibiting TRPV4-mediated ion currents. This compound demonstrates protective effects in models of acute lung injury, making it a valuable tool for research focused on respiratory diseases and cellular calcium signaling. Its specificity for the TRPV4 channel highlights its potential in studying TRPV4-related physiological and pathological processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	2918803-89-9
Applications	TRPV4 Antagonist
Formula	C₂₈H₃₂Cl₂N₆O
Molecular Weight	539.50
SMILES	N#CC1(CCC1)C2=CC=C(N3CCC(CC3)N4C(NC(C)C)=NC5=C(NC(C)=O)C(Cl)=C(Cl)C=C54)C=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.