Documents & Downloads

Trypanothione synthetase-IN-2

TryS Inhibitor

Trypanothione synthetase-IN-2 is a competitive inhibitor of trypanothione synthetase (TryS) in Leishmania infantum, exhibiting an IC50 value of 5.4 μM when using triamine spermidine as the polyamine substrate. This compound serves as a valuable tool for studying the role of TryS in trypanothione metabolism and presents potential applications in the development of therapeutics against leishmaniasis. Its inhibition of TryS can aid in investigating the biochemical pathways crucial for Leishmania survival and pathology.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3033799-60-6
Applications	TryS Inhibitor
Formula	C₄₁H₆₉N₇O₁₁
Molecular Weight	836.03
SMILES	O=C(C1=CC(OCCN)=C(C(OCCN)=C1)OCCN)OCC(COC(C2=CC(OCCN)=C(C(OCCN)=C2)OCCN)=O)NC(CCCCCCCCCCC)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.