Fig. 1 · Structure
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TS-021 free base
Dipeptidyl Peptidase Inhibitor
TS-021 free base is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV), a serine protease with a crucial role in glucose metabolism and immune regulation, exhibiting an IC50 of 4.6 nM. This compound is of significant interest in diabetes research and immune modulation studies, as DPP-IV inhibitors can enhance insulin secretion and improve glycemic control. TS-021 free base is valuable for investigations aimed at understanding DPP-IV's role in metabolic disorders and therapeutic applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 625110-37-4 |
| Applications | Dipeptidyl Peptidase Inhibitor |
| Formula | C11H18FN3O2 |
| Molecular Weight | 243.28 |
| Synonyms | DPP-IV-IN-1 |
| SMILES | N#C[C@H]1N(C(CNC(C)(C)CO)=O)C[C@@H](F)C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.