TTBK1-IN-4

Catalog No.: A79357
TTBK1 Inhibitor
TTBK1-IN-4 is a potent inhibitor of TTBK1, exhibiting a biochemical IC₅₀ of 2.3 nM and a cellular IC₅₀ of 42 nM. This compound serves as a valuable tool for investigating the role of TTBK1 in neurodegenerative diseases, particularly Alzheimer's disease. Researchers can utilize TTBK1-IN-4 to explore its potential therapeutic implications and the underlying mechanisms associated with TTBK1 activity.
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5mg
10mg
50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTTBK1-IN-4 is a potent inhibitor of TTBK1, exhibiting a biochemical IC₅₀ of 2.3 nM and a cellular IC₅₀ of 42 nM. This compound serves as a valuable tool for investigating the role of TTBK1 in neurodegenerative diseases, particularly Alzheimer's disease. Researchers can utilize TTBK1-IN-4 to explore its potential therapeutic implications and the underlying mechanisms associated with TTBK1 activity.
Product Information
Catalog NumA79357
FormulaC17H17N5O
Molecular Weight307.35
CAS Number2735015-54-8
SMILESCC[C@](C)(O)C#CC1=NC=C2C=CN(C3=NC(N)=NC=C3)C2=C1
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