TTBK1/2-IN-2 is a selective inhibitor of Tau tubulin kinase 1 (TTBK1) and TTBK2, exhibiting IC50 values of 384 nM and 175 nM, respectively. This compound has been shown to significantly influence ciliogenesis in human induced pluripotent stem cells (iPSCs), making it a valuable tool for studying the roles of TTBK1 and TTBK2 in cellular processes and related pathologies. Its potent inhibitory activity positions TTBK1/2-IN-2 as an important reagent for research in neurodegenerative diseases and cilia-related disorders.
TTBK1/2-IN-2 is a selective inhibitor of Tau tubulin kinase 1 (TTBK1) and TTBK2, exhibiting IC50 values of 384 nM and 175 nM, respectively. This compound has been shown to significantly influence ciliogenesis in human induced pluripotent stem cells (iPSCs), making it a valuable tool for studying the roles of TTBK1 and TTBK2 in cellular processes and related pathologies. Its potent inhibitory activity positions TTBK1/2-IN-2 as an important reagent for research in neurodegenerative diseases and cilia-related disorders.
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