TVB-3664
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | TVB-3664 is an orally available, reversible, potent, selective and highly bioavailable fatty acid synthase (FASN) inhibitor, with IC50 values of 18 nM and 12 nM for human and mouse cell palmitate synthesis, respectively. TVB-3664 significantly reduces tubulin palmitoylation and mRNA expression. |
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Catalog Num | A18829 |
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Formula | C25H23F3N4O2 |
Molecular Weight | 468.47 |
CAS Number | 2097262-58-1 |
SMILES | CC1=C(C=C(C(C)=C1)C(N2CC(C2)C3=CC=C(C=C3)C#N)=O)C4=C(N=C(N4)C(F)(F)F)COC |
Synonyms | TVB-3664; TVB 3664; TVB3664. |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 86 mg/mL (183.57 mM) | |
Water | Insoluble | ||
Ethanol | 46 mg/mL (98.19 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 21.35 mL | 106.73 mL | 213.46 mL |
0.5 mM | 4.27 mL | 21.35 mL | 42.69 mL |
1 mM | 2.13 mL | 10.67 mL | 21.35 mL |
5 mM | 0.43 mL | 2.13 mL | 4.27 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2