Tyr6,D-Phe7,D-His9-Substance P (6-11)

Name: [Tyr6,D-Phe7,D-His9]-Substance P (6-11)
Brand: Adooq Bioscience
SKU: A62035
Rating: 5 (288 reviews)

Catalog No.: A62035

Tachykinin NK1 Receptor Antagonist

[Tyr6,D-Phe7,D-His9]-Substance P (6-11) is a potent antagonist of the tachykinin NK1 receptor. This compound effectively inhibits hyperalgesia induced by histamine, making it valuable for research into pain pathways and the mechanisms of nociception. Its application extends to studies investigating the role of tachykinins in various biological processes and pain modulation.

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[Tyr6,D-Phe7,D-His9]-Substance P (6-11) 145194-26-9 Tachykinin NK1 Receptor Antagonist

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Biological Activity

Description	[Tyr6,D-Phe7,D-His9]-Substance P (6-11) is a potent antagonist of the tachykinin NK1 receptor. This compound effectively inhibits hyperalgesia induced by histamine, making it valuable for research into pain pathways and the mechanisms of nociception. Its application extends to studies investigating the role of tachykinins in various biological processes and pain modulation.

Product Information

Catalog Num	A62035
Formula	C44H57N9O7S
Molecular Weight	856.04
CAS Number	145194-26-9
Sequence	Tyr-{d-Phe}-Phe-{d-His}-Leu-Met-NH2
Sequence shortening	Y-{d-Phe}-F-{d-His}-LM-NH2
SMILES	CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC([C@@H](CC1=CN=CN1)NC([C@@H](NC([C@H](NC([C@@H](N)CC2=CC=C(C=C2)O)=O)CC3=CC=CC=C3)=O)CC4=CC=CC=C4)=O)=O)=O

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