U-89360E is a selective inhibitor of HIV-1 protease, demonstrating potent activity against the wildtype strain as well as the V82D and V82N mutants, with inhibitory constants (Ki) of 20 nM, 560 nM, and 2100 nM, respectively. Its effectiveness against multiple viral variants makes it a valuable tool for antiviral research and the development of therapeutic strategies targeting HIV-1. U-89360E is particularly relevant for studies focusing on resistance patterns and protease inhibition in the context of HIV treatment.
U-89360E is a selective inhibitor of HIV-1 protease, demonstrating potent activity against the wildtype strain as well as the V82D and V82N mutants, with inhibitory constants (Ki) of 20 nM, 560 nM, and 2100 nM, respectively. Its effectiveness against multiple viral variants makes it a valuable tool for antiviral research and the development of therapeutic strategies targeting HIV-1. U-89360E is particularly relevant for studies focusing on resistance patterns and protease inhibition in the context of HIV treatment.
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