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UA2239

Antimalarial Agent

UA2239 is an antimalarial agent that functions as an acyclic nucleoside phosphonate. It disrupts the critical cGMP-dependent egress pathway by lowering cGMP levels, specifically targeting guanylyl cyclase α. UA2239 exhibits rapid and irreversible inhibitory effects on Plasmodium parasites, making it a valuable compound for research into malaria treatments and mechanisms.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2455422-89-4
Applications	Antimalarial Agent
Formula	C₉H₁₂N₅Na₂O₅P
Molecular Weight	347.18
SMILES	O=C1NC(N)=NC2=C1N=CN2CC[C@H](CP(O[Na])(O[Na])=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.