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UAMC 00039 dihydrochloride is a potent inhibitor of dipeptidyl peptidase II (DPP-II) (IC50 = 0.48 nM). Exhibits selectivity for DPP-II against DPP-9, DPP-8 and DPP-IV (IC50 values are 78.6, 142 and 165 μM, respectively).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.13 mL | 130.63 mL | 261.26 mL |
| 0.5 mM | 5.23 mL | 26.13 mL | 52.25 mL |
| 1 mM | 2.61 mL | 13.06 mL | 26.13 mL |
| 5 mM | 0.52 mL | 2.61 mL | 5.23 mL |
*The above data is based on the productmolecular weight 382.76. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16047 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 697797-51-6 |
| Formula | C16H24ClN3O.2HCl |
| M. Wt | 382.76 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | Uamc00039 dihydrochloride |
| SMILES | ClC1=CC=C(C=C1)CNCC[[email protected]@H](C(N2CCCCC2)=O)N.Cl.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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