UAWJ246 is a covalent reversible inhibitor targeting the SARS-CoV-2 main protease (Mpro), exhibiting an IC50 of 0.045 μM and a Ki of 0.036 μM. This compound demonstrates significant antiviral activity by effectively inhibiting SARS-CoV-2 viral replication while maintaining low cytotoxicity. UAWJ246 is suitable for research focused on SARS-CoV-2 infection and the development of therapeutic strategies for COVID-19.
UAWJ246 is a covalent reversible inhibitor targeting the SARS-CoV-2 main protease (Mpro), exhibiting an IC50 of 0.045 μM and a Ki of 0.036 μM. This compound demonstrates significant antiviral activity by effectively inhibiting SARS-CoV-2 viral replication while maintaining low cytotoxicity. UAWJ246 is suitable for research focused on SARS-CoV-2 infection and the development of therapeutic strategies for COVID-19.
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