Ubenimex

Catalog No.: A10958

reversible Protease inhibitor

Ubenimex Chemical Structure

CAS NO. 58970-76-6

Ubenimex, also known as NK 421 and Bestatin, is a CD13 inhibitor. Ubenimex attenuates acquired sorafenib resistance in renal cell carcinoma by inhibiting Akt signaling in a lipophagy associated mechanism. Ubenimex synergistically enhances the effects of anticancer drugs in hepatocellular carcinoma. Ubenimex inhibits cell proliferation, migration and invasion by inhibiting the expression of APN and inducing autophagic cell death in prostate cancer cells.

Availability: In stock

Package Price Qty
25 mg
$150.00
100 mg
$330.00
200 mg
$550.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Ubenimex, also known as NK 421 and Bestatin, is a CD13 inhibitor. Ubenimex attenuates acquired sorafenib resistance in renal cell carcinoma by inhibiting Akt signaling in a lipophagy associated mechanism. Ubenimex synergistically enhances the effects of anticancer drugs in hepatocellular carcinoma. Ubenimex inhibits cell proliferation, migration and invasion by inhibiting the expression of APN and inducing autophagic cell death in prostate cancer cells.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.43 mL 162.14 mL 324.28 mL
0.5 mM 6.49 mL 32.43 mL 64.86 mL
1 mM 3.24 mL 16.21 mL 32.43 mL
5 mM 0.65 mL 3.24 mL 6.49 mL

*The above data is based on the productmolecular weight 308.378. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10958
Actions Inhibitor
M. Wt 308.378
Formula C16H24N2O4
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 58970-76-6
Synonyms Ubenimex, NK 421, NK-421, NK421, Bestatin, NSC 265489, NSC265489, NSC-265489
SMILES CC(C)C[[email protected]@H](C(O)=O)NC([[email protected]@H](O)[[email protected]](N)CC1=CC=CC=C1)=O

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