UC-112 is a selective modulator of survivin and XIAP, with notable anticancer properties. It induces the degradation of survivin through the ubiquitin-mediated proteasomal pathway, while also decreasing XIAP levels in in vivo tumor models. This compound activates caspase-3/7 and caspase-9, promoting apoptosis in cancer cells. UC-112 is relevant for research into melanoma, prostate cancer, and various cancer-related studies.
UC-112 is a selective modulator of survivin and XIAP, with notable anticancer properties. It induces the degradation of survivin through the ubiquitin-mediated proteasomal pathway, while also decreasing XIAP levels in in vivo tumor models. This compound activates caspase-3/7 and caspase-9, promoting apoptosis in cancer cells. UC-112 is relevant for research into melanoma, prostate cancer, and various cancer-related studies.
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