UCM 549

Catalog No.: A61729
MT2 Inverse Agonist/MT1 Antagonist
UCM 549 is an inverse agonist of the melatonin MT2 receptor and an antagonist of the MT1 receptor. This compound modulates melatonin signaling pathways, making it a valuable tool for investigating sleep disorders and circadian rhythm regulation. Its application extends to studies focused on the role of melatonin receptors in neuroprotection and mood regulation.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionUCM 549 is an inverse agonist of the melatonin MT2 receptor and an antagonist of the MT1 receptor. This compound modulates melatonin signaling pathways, making it a valuable tool for investigating sleep disorders and circadian rhythm regulation. Its application extends to studies focused on the role of melatonin receptors in neuroprotection and mood regulation.
Product Information
Catalog NumA61729
FormulaC19H21NO2
Molecular Weight295.38
CAS Number753502-19-1
SMILESCC(NCC1C2=CC(OC)=CC=C2CC3=CC=CC=C3C1)=O
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