UCM 793 is a potent non-selective agonist of the MT1 and MT2 melatonin receptors, exhibiting pKis of 9.09 and 9.19, respectively. This compound is known to enhance the frequency of wakefulness episodes while reducing their duration, thereby influencing the quality of vigilance states. Importantly, UCM 793 facilitates a decrease in sleep onset without adversely affecting the maintenance of non-REM sleep, making it a valuable tool for research in sleep disorders and circadian rhythm studies.
UCM 793 is a potent non-selective agonist of the MT1 and MT2 melatonin receptors, exhibiting pKis of 9.09 and 9.19, respectively. This compound is known to enhance the frequency of wakefulness episodes while reducing their duration, thereby influencing the quality of vigilance states. Importantly, UCM 793 facilitates a decrease in sleep onset without adversely affecting the maintenance of non-REM sleep, making it a valuable tool for research in sleep disorders and circadian rhythm studies.
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