Fig. 1 · Structure
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UDP-glucosamine disodium
O-GlcNAc Transferase Substrate
UDP-glucosamine disodium serves as a substrate for O-GlcNAc transferase, facilitating the conjugation of O-GlcNAc to target proteins. This modification plays a crucial role in various cellular processes, including signal transduction and transcriptional regulation. Additionally, UDP-glucosamine is produced via the hexosamine biosynthesis pathway, which is primarily controlled by glucose-6-phosphate and the enzyme GFAT. Its applications in research include studying O-GlcNAcylation dynamics and investigating the implications of glycosylation in cellular functions and disease mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 1355005-51-4 |
| Applications | O-GlcNAc Transferase Substrate |
| Formula | C15H23N3Na2O16P2 |
| Molecular Weight | 609.28 |
| SMILES | O[C@H]1[C@@](N2C(NC(C=C2)=O)=O)([H])O[C@@H]([C@H]1O)COP(OP(O[C@H]3O[C@@H]([C@H]([C@@H]([C@H]3N)O)O)CO)(O[Na])=O)(O[Na])=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.