UMB-32 is a potent and selective BRD4 inhibitor, binding to BRD4 with a Kd of 550 nM and an IC50 of 637 nM. It also demonstrates activity against TAF1, a bromodomain-containing transcription factor.
UMB-32 is a potent and selective BRD4 inhibitor, binding to BRD4 with a Kd of 550 nM and an IC50 of 637 nM. It also demonstrates activity against TAF1, a bromodomain-containing transcription factor.
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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