BRD4-IN-4

Catalog No.: A40500
BRD4 Inhibitor
BRD4-IN-4 is a selective inhibitor of the bromodomain-containing protein 4 (BRD4) with an IC50 of 6.83 μM. This compound effectively inhibits the proliferation of MV4-11 cells and induces cell cycle arrest in the G1 phase. BRD4-IN-4 is primarily utilized in research focused on MLL leukemia, providing insights into the therapeutic potential of targeting BRD4 in cancer treatment.
Grouped product items
Size Price Stock Qty
5mg
$20.00
In stock
10mg
$25.00
In stock
25mg
$40.00
In stock
50mg
$60.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBRD4-IN-4 is a selective inhibitor of the bromodomain-containing protein 4 (BRD4) with an IC50 of 6.83 μM. This compound effectively inhibits the proliferation of MV4-11 cells and induces cell cycle arrest in the G1 phase. BRD4-IN-4 is primarily utilized in research focused on MLL leukemia, providing insights into the therapeutic potential of targeting BRD4 in cancer treatment.
Product Information
Catalog NumA40500
FormulaC17H18N2O3S
Molecular Weight330.40
CAS Number304685-40-3
SMILESO=C1C2=CC=CC3=C(S(=O)(N4CCCC4)=O)C=CC(N1CC)=C32
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