Undecane is a potent cAMP agonist known for its anti-allergic and anti-inflammatory properties. It effectively inhibits degranulation and the release of key inflammatory mediators such as histamine and TNF-α. Additionally, undecane reverses the phosphorylation of p38, modulates NF-κB transcriptional activity, and targets cytokine and chemokine gene expression, including TARC, MDC, and IL-8. This compound is valuable for investigations into skin inflammatory disorders, particularly atopic dermatitis.
Undecane is a potent cAMP agonist known for its anti-allergic and anti-inflammatory properties. It effectively inhibits degranulation and the release of key inflammatory mediators such as histamine and TNF-α. Additionally, undecane reverses the phosphorylation of p38, modulates NF-κB transcriptional activity, and targets cytokine and chemokine gene expression, including TARC, MDC, and IL-8. This compound is valuable for investigations into skin inflammatory disorders, particularly atopic dermatitis.
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