Fig. 1 · Structure
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UP12
VCP Activator
UP12 is a valosin-containing protein (VCP) activator that enhances ATPase activity with an EC50 of 1.24 μM. This compound plays a crucial role in modulating protein homeostasis and is valuable for research applications exploring cellular stress responses and protein degradation pathways. Its ability to potentiate VCP activity makes it a significant tool for studies in proteostasis and related therapeutic areas.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 443353-87-5 |
| Applications | VCP Activator |
| Formula | C23H16ClN3O3S |
| Molecular Weight | 449.91 |
| SMILES | O=C(C1=CC=CC=C1)NN2C(SCC(C3=CC=C(C=C3)Cl)=O)=NC4=C(C2=O)C=CC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.