Fig. 1 · Structure
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UPCDC30766
p97 Inhibitor
UPCDC30766 is a potent allosteric inhibitor of p97, exhibiting an IC50 value of 12 nM and an EC50 of 0.23 μM in cellular assays. This compound serves as a valuable tool for cancer research, particularly in the study of colon cancer pathways. Its selective inhibition of p97 may provide insights into the mechanisms underlying tumorigenesis and therapeutic resistance.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2152623-68-0 |
| Applications | p97 Inhibitor |
| Formula | C30H32F2N6O3S |
| Molecular Weight | 594.68 |
| SMILES | O=C(OCC#CC1=C(F)C=C(OCC2=NN=C(S[C@H]3C=CCCC3)N2C4=CC=CN=C4)C(F)=C1)NC5CCN(C)CC5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.