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UPGL00004 is a potent allosteric glutaminase C (GAC) inhibitor (IC50=29 nM; Kd=27 nM). UPGL00004 strongly inhibits the proliferation of highly aggressive triple-negative breast cancer cell lines.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.7 mL | 93.52 mL | 187.03 mL |
| 0.5 mM | 3.74 mL | 18.7 mL | 37.41 mL |
| 1 mM | 1.87 mL | 9.35 mL | 18.7 mL |
| 5 mM | 0.37 mL | 1.87 mL | 3.74 mL |
*The above data is based on the productmolecular weight 534.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A19047 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 534.66 |
| Formula | C25H26N8O2S2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1890169-95-5 |
| Synonyms | UPGL 00004, UPGL-00004 |
| SMILES | O=C(NC1=NN=C(N2CCC(NC3=NN=C(NC(CC4=CC=CC=C4)=O)S3)CC2)S1)CC5=CC=CC=C5 |
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