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Urease-IN-10

Urease Inhibitor

Urease-IN-10 is a competitive inhibitor of urease, demonstrating an IC50 value of 3.59±0.07 μM and a Ki of 7.45 μM. This compound is a conjugate of Diclofenac and Sulfanilamide, effectively inhibiting Jack bean urease (JBU) through competitive binding. Urease-IN-10 is valuable for research applications focused on urease-related biochemical processes and potential therapeutic interventions targeting urease in various disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1012205-70-7
Applications	Urease Inhibitor
Formula	C₂₀H₁₇Cl₂N₃O₃S
Molecular Weight	450.34
SMILES	O=S(C1=CC=C(NC(CC2=CC=CC=C2NC3=C(Cl)C=CC=C3Cl)=O)C=C1)(N)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.