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Urease-IN-20

Urease Inhibitor

Urease-IN-20 is a potent inhibitor of urease, specifically targeting Helicobacter pylori (H. pylori) with an IC50 value of 0.14 μM. This compound not only inhibits H. pylori growth but also reduces apoptosis, reactive oxygen species (ROS), and γH2AX levels in GES-1 cells infected with the bacterium. Additionally, Urease-IN-20 demonstrates significant protective effects on gastric mucosa, highlighting its potential for research in H. pylori-related pathologies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2998940-98-8
Applications	Urease Inhibitor
Formula	C₁₄H₈FNO₂Se
Molecular Weight	320.18
SMILES	O=C(C1=CC=CC(F)=C1)OC2=N[Se]C3=CC=CC=C32

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.