Fig. 1 · Structure
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USP1-IN-2
USP1 Inhibitor
USP1-IN-2 is a selective inhibitor of ubiquitin-specific protease 1 (USP1), with an IC50 of approximately 50 nM. This compound is valuable for investigating the role of USP1 in cancer biology, particularly in osteosarcoma research. By inhibiting USP1, it contributes to studies on proteostasis and the regulation of DNA damage repair processes, making it a critical tool for understanding cancer progression and potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2098212-05-4 |
| Applications | USP1 Inhibitor |
| Formula | C26H22F4N6O |
| Molecular Weight | 510.49 |
| SMILES | O=C1NC2=CN=C(C3=C(C(C)C)C(F)=CC=C3)N=C2N1CC4=CC=C(C5=NC(C(F)(F)F)=CN5C)C=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.