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USP1-IN-4

USP1 Inhibitor

USP1-IN-4 is a potent inhibitor of USP1, exhibiting an IC50 value of 2.44 nM. This compound demonstrates significant anticancer activity and shows synergistic effects when used in combination with various standard anticancer therapies. It serves as a valuable tool for research focused on cancer treatment and the modulation of deubiquitinating enzyme pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2878441-72-4
Applications	USP1 Inhibitor
Formula	C₂₆H₂₃F₃N₆
Molecular Weight	476.50
SMILES	FC(F)(C1=CN(C)C(C2=CC=C(CC3=NC=C4C=NC(C5=C(C(C)C)C=CC=C5)=NN43)C=C2)=N1)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.