Fig. 1 · Structure

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USP1-IN-5

USP1 Inhibitor

USP1-IN-5 is a potent inhibitor of Ubiquitin-specific protease 1 (USP1) with an IC50 of less than 50 nM. This compound demonstrates significant anti-proliferative activity in MDA-MB-436 breast cancer cells, also with an IC50 of less than 50 nM. USP1-IN-5 is valuable for research in cancer biology and therapeutic studies targeting USP1-related pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2925547-94-8
Applications USP1 Inhibitor
Formula C27H23F3N8O
Molecular Weight 532.52
SMILES
FC(F)(C1=CN(C)C(C23C4C5C2C6C3C4C65CN7N=CC8=C7N=C(C9=C(C%10CC%10)N=CN=C9OC)N=C8)=N1)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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