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USP1-IN-6

USP1 Inhibitor

USP1-IN-6 is a potent inhibitor of the deubiquitinating enzyme USP1, exhibiting an IC50 of less than 50 nM. This compound effectively disrupts USP1 activity, leading to increased levels of ubiquitinated proteins. USP1-IN-6 is valuable in research focused on the regulation of protein degradation and its implications in cancer biology, particularly in the study of MDA-MB-436 cell lines.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2925547-95-9
Applications	USP1 Inhibitor
Formula	C₂₉H₂₇F₃N₈O
Molecular Weight	560.57
SMILES	FC(F)(C1=CN(C(C)C)C(C23C4C5C2C6C3C4C65CN7N=CC8=C7N=C(C9=C(C%10CC%10)N=CN=C9OC)N=C8)=N1)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.