Fig. 1 · Structure
Documents & Downloads
USP1-IN-7
USP1 Inhibitor
USP1-IN-7 is a selective inhibitor of ubiquitin-specific peptidase 1 (USP1) and its cofactor UAF1, exhibiting an IC50 of ≤50 nM. This compound effectively inhibits the proliferation of MDA-MB-436 breast cancer cells, making it a valuable tool for studying the role of USP1 in cancer biology. Its potent activity positions USP1-IN-7 as a promising candidate for research applications targeting the regulation of deubiquitination processes.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3033480-42-8 |
| Applications | USP1 Inhibitor |
| Formula | C27H23F4N7O2 |
| Molecular Weight | 553.51 |
| SMILES | CN(C1=CN=C(C(F)=C1N2CC3=CC=C(C4=NC(C(F)(F)F)=CN4C)C=C3)C5=C(OC)N=CN=C5C6CC6)C2=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.