Documents & Downloads

USP1-IN-8

USP1 Inhibitor

USP1-IN-8 is a potent inhibitor of ubiquitin-specific peptidase 1 (USP1) and its cofactor UAF1, exhibiting an IC50 of ≤50 nM. This compound effectively inhibits the proliferation of MDA-MB-436 breast cancer cells, making it a valuable tool for investigating USP1's role in cancer biology. Its precise targeting of the USP1-UAF1 complex positions USP1-IN-8 as an important reagent for research in therapeutic strategies involving deubiquitination and related pathways.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3033480-77-9
Applications	USP1 Inhibitor
Formula	C₂₉H₂₄D₃F₄N₇O₂
Molecular Weight	584.58
SMILES	O=C1N(CC2=CC=C(C3=NC(C(F)(F)F)=CN3C(C)C)C=C2)C4=C(F)C(C5=C(OC)N=CN=C5C6CC6)=NC=C4N1C([2H])([2H])[2H]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.