Fig. 1 · Structure
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USP30-IN-1
USP30 Inhibitor
USP30-IN-1 is a selective inhibitor of the deubiquitinating enzyme USP30, exhibiting an IC50 value of 94 nM. This compound is valuable in research focusing on diseases associated with impaired mitophagy, as it modulates USP30’s activity to enhance mitochondrial quality control mechanisms. Its application aids in the study of cellular processes related to mitochondrial dysfunction and potential therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2511541-78-7 |
| Applications | USP30 Inhibitor |
| Formula | C17H15N5O2 |
| Molecular Weight | 321.33 |
| SMILES | N#CC1=CC=CC(C2=CN=C(C(N[C@@H]3C[C@@H](C)N(C#N)C3)=O)O2)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.