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USP7-IN-16

USP7 Inhibitor

USP7-IN-16 is a selective inhibitor of USP7, demonstrating an IC50 of 5.5 nM in the FLINT assay and 2.1 nM in MM.1S cells. This compound exhibits significant antitumor activity in vivo, positioning it as a valuable tool for research in oncology. Its efficacy in targeting USP7 makes it an important candidate for studies focused on cancer biology and therapeutic development.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2166587-77-3
Applications	USP7 Inhibitor
Formula	C₄₃H₄₅N₇O₆S
Molecular Weight	787.93
SMILES	O=C1C2=C(N=CN1CC3(CCN(CC3)C([C@H]4[C@H](C5=CC=CC=C5)CN(CC4)C(C6=C(C)N=C(C7=CN=C(C)C=C7)S6)=O)=O)O)N(C8=CC(OC)=CC(OC)=C8)C=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.